{"id":546,"title":"Scientists discover a surprising clue to autism's origins hidden in the placenta","title_zh":"胎盘中的炎症与损伤线索或可解释雄性小鼠自闭样特征","url":"https://sciencedaily.com/releases/2026/11/261102202824.htm","doi":null,"pmid":null,"journal":"Pregnancy and Childbirth News -- ScienceDaily","kind":"news","lang":"en","published_at":"2026-11-03T12:41:49+00:00","fetched_at":"2026-11-08T03:45:26+00:00","authors":[],"primary_topic":"endometrium","topics":[{"slug":"endometrium","score":4.0,"hits":["placenta","placental"]}],"topic_score":4.0,"preference_score":0.0,"preference_labels":[],"llm_score":66.0,"final_score":63.0,"score_dims":{"novelty":74,"rigor":50,"impact":62,"relevance":58,"translation":52},"recommend_reason":"内容涉及孕期炎症、胎盘损伤与后代神经发育的性别差异，对生殖免疫和早期妊娠研究有启发；但作为新闻稿信息有限，且与ART核心环节关联边缘，适合浏览追踪。","keywords":["孕期炎症","胎盘损伤","自闭症","性别差异","神经发育","小鼠模型"],"selected":0,"story_id":110,"llm_provider":"deepseek","llm_model":"deepseek-flash","llm_effort":"low","source_key":"rss-sciencedaily-pregnancy","source_name":"ScienceDaily · Pregnancy（领域过滤）","source_tier":3,"mention_count":1,"has_interpretation":false,"journal_key":null,"journal_tier":"unknown","journal_if":null,"is_mock":false,"summary_zh":"ScienceDaily报道，一项小鼠研究提示孕期炎症、胎盘损伤与雄性后代自闭样特征之间存在关联，而雌性似乎具有天然保护。该发现被认为可能有助于解释自闭症在男孩中诊断更频繁的现象，并为早期干预提供新思路。原文为新闻摘要，未披露样本量、具体炎症模型、胎盘损伤指标及行为学验证细节，结论需以原始研究为准。","summary":"Scientists have uncovered an unexpected connection between inflammation during pregnancy, placental damage, and autism-like traits in male mice, while females appeared naturally protected. The discovery could help explain why autism is diagnosed more frequently in boys and reveal new opportunities for early intervention.","interpretation_basis":null,"fulltext_status":null,"interpretation":null,"fulltext":{"available":false,"status":null,"reason":"尚未抓取全文（未入选、分数未达阈值，或还没跑 fulltext 步骤）","pmcid":null,"license":null,"chars":0,"source":null,"fetched_at":null}}