{"id":504,"title":"Strong hydrogels through precisely oriented crystallization regulation","title_zh":"通过精准取向结晶调控制备高强度水凝胶","url":"https://doi.org/10.1038/s41467-026-79005-7","doi":"10.1038/s41467-026-79005-7","pmid":null,"journal":"Nature Communications","kind":"paper","lang":"en","published_at":"2026-11-05T00:00:00+00:00","fetched_at":"2026-11-08T03:45:21+00:00","authors":["Langchen Yan","Yan Wang","Chenxi Li","Jian Zhao","Hong Zhang","Yumei Gong","Jing Guo","Yike Li","Shengfa Wang","Jiefeng Gao"],"primary_topic":"ethics-policy","topics":[{"slug":"ethics-policy","score":3.0,"hits":["regulation"]}],"topic_score":3.0,"preference_score":0.0,"preference_labels":[],"llm_score":25.0,"final_score":33.0,"score_dims":{"novelty":80,"rigor":75,"impact":5,"relevance":3,"translation":5},"recommend_reason":"材料科学领域方法新颖、数据扎实，但与生殖医学、辅助生殖及胚胎多组学无直接关联，对本领域读者优先级很低。","keywords":["结晶水凝胶","取向结晶","超拉伸","力学强度","热塑性加工"],"selected":0,"story_id":null,"llm_provider":"deepseek","llm_model":"deepseek-flash","llm_effort":"low","source_key":"crossref-cns","source_name":"Crossref · CNS 与大子刊新上线（领域过滤）","source_tier":1,"mention_count":1,"has_interpretation":false,"journal_key":"nat-commun","journal_tier":"cns-sub","journal_if":14.7,"is_mock":false,"summary_zh":"研究受工业热塑性加工启发，提出ASGS策略，集成碱诱导链活化、超拉伸取向与甘油-海水致密化，以精准调控结晶水凝胶的结晶架构。所得全水合水凝胶拉伸强度达160.0 MPa、模量746.0 MPa、断裂能26.4 kJ·m⁻²；相应塑性体拉伸强度414.2 MPa并保持柔性。该工作为承重及严苛水下工程提供可扩展的强韧稳定结晶水凝胶制备范式。","summary":"Abstract Achieving high mechanical strength and environmental stability is critical for hydrogels in demanding engineering scenarios. Crystalline hydrogels hold promise because their crystallites act as physical crosslinks and energy dissipators; however, precise control over crystalline architecture remains underexplored. Inspired by industrial thermoplastic processing, we report an ASGS strategy for crystalline hydrogels that integrates alkali-induced chain activation (A), ultra-stretching-driven orientation (S), and glycerol-seawater-mediated densification (GS). Alkali treatment yields moderate initial crystallinity with refined nascent crystallites. Ultra-stretching establishes a highly oriented chain network, and subsequent densification achieves maximum crystallinity and highly oriented crystallites. The resultant hydrogels, in the fully hydrated state, combine a tensile strength of 160.0 MPa, a modulus of 746.0 MPa, and a fracture energy of 26.4 kJ·m⁻². The corresponding plastic reaches 414.2 MPa tensile strength while retaining flexibility. This thermoplastic-inspired crystallization engineering provides a scalable paradigm for fabricating strong and stable crystalline hydrogels, promising for load-bearing and harsh underwater engineering applications.","interpretation_basis":null,"fulltext_status":null,"interpretation":null,"fulltext":{"available":false,"status":null,"reason":"尚未抓取全文（未入选、分数未达阈值，或还没跑 fulltext 步骤）","pmcid":null,"license":null,"chars":0,"source":null,"fetched_at":null}}