{"id":484,"title":"Oral-transdermal versus oral oestrogen: outcomes and live birth predictive model for artificial cycle suboptimal endometrial response","title_zh":"口服-经皮联合雌激素与口服雌激素在人工周期子宫内膜反应欠佳患者中的结局比较及活产预测模型","url":"https://doi.org/10.1016/j.rbmo.2026.106065","doi":"10.1016/j.rbmo.2026.106065","pmid":null,"journal":"Reproductive BioMedicine Online","kind":"paper","lang":"en","published_at":"2026-11-01T00:00:00+00:00","fetched_at":"2026-11-08T03:44:35+00:00","authors":["Xinyi Song","Shiheng Zhu","Jing Li","Wei Zhou","Tianxiang Ni","Junhao Yan","Qian Zhang"],"primary_topic":"art-clinical","topics":[{"slug":"art-clinical","score":3.0,"hits":["live birth"]},{"slug":"endometrium","score":3.0,"hits":["endometrial"]},{"slug":"ai-compute","score":3.0,"hits":["predictive model"]}],"topic_score":3.0,"preference_score":0.0,"preference_labels":[],"llm_score":72.0,"final_score":72.0,"score_dims":{"novelty":70,"rigor":60,"impact":70,"relevance":95,"translation":80},"recommend_reason":"人工周期子宫内膜反应欠佳是临床常见难点，比较雌激素给药途径并建立活产预测模型具有直接转化价值；但当前仅有研究问题、缺少结果与设计细节，需阅读全文后再判断证据强度。","keywords":["人工周期","子宫内膜反应","雌激素给药途径","活产预测模型","辅助生殖","临床结局"],"selected":1,"story_id":225,"llm_provider":"deepseek","llm_model":"deepseek-flash","llm_effort":"low","source_key":"crossref-core-journals","source_name":"Crossref · 核心期刊新上线","source_tier":1,"mention_count":2,"has_interpretation":false,"journal_key":"rbmo","journal_tier":"standard","journal_if":3.7,"is_mock":false,"summary_zh":"该研究聚焦人工周期中子宫内膜反应欠佳的患者，比较口服-经皮联合雌激素与单纯口服雌激素两种方案，并构建活产预测模型。原文仅给出研究问题，未提供样本量、设计类型、主要结局数据及模型性能等结果信息，因而无法判断两种方案的优劣及模型可靠性。主题与辅助生殖临床决策和子宫内膜准备密切相关，值得关注全文结果。","summary":"In patients with suboptimal endometrial response during artificial cycle, do reproductive outcomes differ with the use of combined oral-transdermal versus oral oestrogen?","interpretation_basis":null,"fulltext_status":null,"interpretation":null,"fulltext":{"available":false,"status":null,"reason":"尚未抓取全文（未入选、分数未达阈值，或还没跑 fulltext 步骤）","pmcid":null,"license":null,"chars":0,"source":null,"fetched_at":null}}