{"id":408,"title":"How the brain changes during menopause-and why we still don't know what it means","title_zh":"绝经期大脑如何变化——以及为何其意义仍不明确","url":"https://pubmed.ncbi.nlm.nih.gov/42887910","doi":"10.1136/bmj-2026-101144","pmid":"42887910","journal":"BMJ","kind":"paper","lang":"en","published_at":"2026-10-16T00:00:00+00:00","fetched_at":"2026-11-08T03:44:12+00:00","authors":["Willis S"],"primary_topic":"repro-endo","topics":[{"slug":"repro-endo","score":3.0,"hits":["menopause"]}],"topic_score":3.0,"preference_score":0.0,"preference_labels":[],"llm_score":55.0,"final_score":61.0,"score_dims":{"novelty":35,"rigor":20,"impact":45,"relevance":55,"translation":25},"recommend_reason":"作为BMJ的报道性文章，适合了解绝经与脑健康议题及公众沟通；但无原始数据和方法，对ART/胚胎研究无直接指导，不建议作为科研证据精读。","keywords":["绝经","脑改变","生殖内分泌","女性衰老","科普报道"],"selected":1,"story_id":388,"llm_provider":"deepseek","llm_model":"deepseek-flash","llm_effort":"low","source_key":"pubmed-top-journals","source_name":"PubMed · CNS/大子刊/四大医学刊（生殖相关）","source_tier":1,"mention_count":1,"has_interpretation":false,"journal_key":"bmj","journal_tier":"general-top","journal_if":93.6,"is_mock":false,"summary_zh":"该文为BMJ发表的评论/报道性文章，讨论女性绝经期大脑的变化，并指出目前对这些神经改变意味着什么仍缺乏明确认识。原文未提供摘要、研究设计、样本量或具体数据，无法评估其方法学质量与结论强度。文章主题属于生殖内分泌与女性衰老交叉领域，可能有助于临床沟通和科普，但对辅助生殖实验室或胚胎研究的直接转化价值有限。","summary":"","interpretation_basis":null,"fulltext_status":null,"interpretation":null,"fulltext":{"available":false,"status":null,"reason":"尚未抓取全文（未入选、分数未达阈值，或还没跑 fulltext 步骤）","pmcid":null,"license":null,"chars":0,"source":null,"fetched_at":null}}