{"id":250,"title":"Evaluation of Fallopian Tube Patency in Patients With Endometriosis-Induced Infertility by SONAZOID Real-Time Four-Dimensional Salpingography","title_zh":"SONAZOID 实时四维输卵管超声造影评估子宫内膜异位症相关不孕患者的输卵管通畅性","url":"https://pubmed.ncbi.nlm.nih.gov/42978179","doi":"10.1002/jcu.70459","pmid":"42978179","journal":"J Clin Ultrasound","kind":"paper","lang":"en","published_at":"2026-11-03T00:00:00+00:00","fetched_at":"2026-11-08T03:44:00+00:00","authors":["Mao S","Zhang M","Dong W","Qiang Y","Ma Y","Wu Y"],"primary_topic":"art-clinical","topics":[{"slug":"art-clinical","score":4.0,"hits":["infertility"]},{"slug":"endometrium","score":4.0,"hits":["endometriosis"]}],"topic_score":4.0,"preference_score":0.0,"preference_labels":[],"llm_score":72.0,"final_score":72.0,"score_dims":{"novelty":62,"rigor":70,"impact":68,"relevance":88,"translation":80},"recommend_reason":"将四维超声造影与注液峰值压力、疼痛评分等定量指标结合，用于内异症相关不孕的输卵管评估，操作无辐射、临床可及性高，对 ART 前输卵管状态判断有实用参考价值；但为单中心回顾性设计、金标准验证样本量有限（21 条），证据等级中等。","keywords":["子宫内膜异位症","输卵管通畅性","四维子宫输卵管超声造影","SONAZOID","不孕症","峰值压力"],"selected":1,"story_id":146,"llm_provider":"deepseek","llm_model":"deepseek-flash","llm_effort":"low","source_key":"pubmed-uterus-pregnancy","source_name":"PubMed · 内膜/植入/早孕","source_tier":1,"mention_count":1,"has_interpretation":false,"journal_key":null,"journal_tier":"unknown","journal_if":null,"is_mock":false,"summary_zh":"本研究回顾性纳入 100 例子宫内膜异位症相关不孕患者（共 200 条输卵管），采用 SONAZOID 实时四维子宫输卵管超声造影（4D-HyCoSy）评估输卵管通畅性，并按通畅或阻塞程度分为六组；以宫腔镜联合腹腔镜为金标准，同时用注液机记录造影剂注射峰值压力及患者疼痛评分，观察造影剂反流与定量范围。结果显示 4D-HyCoSy 诊断准确率为 95.23%（20/21），双侧阻塞组的峰值压力与疼痛评分显著高于其他组。结论认为 4D-HyCoSy 结合宫腔内峰值压力、疼痛评分及造影剂反流等定量指标，可客观有效地评估内异症相关不孕的输卵管状态，为临床提供影像学参考。","summary":"BACKGROUND: To evaluate SONAZOID real-time four-dimensional hysterosalpingography (4D-HyCoSy) for assessing fallopian tube patency in endometriosis (EM)-induced infertility. METHODS: A retrospective study of 100 patients (200 fallopian tubes) underwent SONAZOID 4D-HyCoSy. Patients were divided into six groups based on varying degrees of tubal patency or obstruction. A liquid injection machine was employed to record the peak pressure for contrast agent injection, and the corresponding pain score of the patients was noted. Contrast agent reflux and quantitative range were observed in each group. Hysteroscopy combined with laparoscopy was considered the gold standard. RESULTS: The diagnostic accuracy of 4D-HyCoSy was 95.23% (20/21) compared to laparoscopy. Peak pressure and pain scores were significantly higher in patients with bilateral obstruction than in the other groups (p 0.8), indicating clinically meaningful differences. CONCLUSION: 4D-HyCoSy, combined with quantitative indicators like intrauterine peak pressure, pain score, and contrast reflux, provides an effective and objective assessment of tubal patency in EM-induced infertility, thereby offering a valuable imaging reference for clinical evaluation of tubal status.","interpretation_basis":null,"fulltext_status":null,"interpretation":null,"fulltext":{"available":false,"status":null,"reason":"尚未抓取全文（未入选、分数未达阈值，或还没跑 fulltext 步骤）","pmcid":null,"license":null,"chars":0,"source":null,"fetched_at":null}}