{"id":241,"title":"Circulating tRNA-derived fragments in women with endometriosis: a pilot study","title_zh":"子宫内膜异位症女性循环 tRNA 衍生片段：一项初步研究","url":"https://pubmed.ncbi.nlm.nih.gov/42980989","doi":"10.1186/s43556-026-00629-8","pmid":"42980989","journal":"Mol Biomed","kind":"paper","lang":"en","published_at":"2026-11-04T00:00:00+00:00","fetched_at":"2026-11-08T03:44:00+00:00","authors":["Vash-Margita A","Surmann H","Mamillapalli R","Taylor HS"],"primary_topic":"endometrium","topics":[{"slug":"endometrium","score":3.0,"hits":["endometriosis"]}],"topic_score":3.0,"preference_score":0.0,"preference_labels":[],"llm_score":60.0,"final_score":60.0,"score_dims":{"novelty":65,"rigor":40,"impact":55,"relevance":75,"translation":50},"recommend_reason":"主题属于子宫内膜异位症与循环小 RNA 标志物，具有一定新颖性和转化潜力；但仅为 pilot 研究且无摘要与数据可核，严谨性和结论强度无法评估，适合浏览追踪而非必读。","keywords":["子宫内膜异位症","tRNA 衍生片段","循环小 RNA","生物标志物","初步研究"],"selected":1,"story_id":82,"llm_provider":"deepseek","llm_model":"deepseek-flash","llm_effort":"low","source_key":"pubmed-uterus-pregnancy","source_name":"PubMed · 内膜/植入/早孕","source_tier":1,"mention_count":1,"has_interpretation":false,"journal_key":null,"journal_tier":"unknown","journal_if":null,"is_mock":false,"summary_zh":"该条目为发表于 Mol Biomed 的论文，标题提示研究子宫内膜异位症女性外周循环中的 tRNA 衍生片段（tRNA-derived fragments）。原文未提供摘要，作者与题目信息显示其为初步（pilot）研究，可能探讨这类小 RNA 片段作为子宫内膜异位症循环标志物的可行性；但由于缺乏样本量、检测平台、对照设置、差异表达结果与验证数据，无法判断其主要发现与结论。","summary":"","interpretation_basis":null,"fulltext_status":null,"interpretation":null,"fulltext":{"available":false,"status":null,"reason":"尚未抓取全文（未入选、分数未达阈值，或还没跑 fulltext 步骤）","pmcid":null,"license":null,"chars":0,"source":null,"fetched_at":null}}